Angiopoietin-Like Protein 2 Induces Synovial Inflammation in the Facet Joint Leading to Degenerative Changes via Interleukin-6 Secretion

Angiopoietin-Like Protein 2 Induces Synovial Inflammation in the Facet Joint Leading to Degenerative Changes via Interleukin-6 Secretion

Study Design Experimental human study. Purpose To determine whether angiopoietin-like protein 2 (ANGPTL2) is highly expressed in the hyperplastic facet joint (FJ) synovium and whether it activates interleukin-6 (IL-6) secretion in FJ synoviocytes. Overview of Literature Mechanical stress-induced syn...

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Bibliographic Details
Main Authors: Kazuki Sugimoto, Takayuki Nakamura, Takuya Tokunaga, Yusuke Uehara, Tatsuya Okada, Takuya Taniwaki, Toru Fujimoto, Yuichi Oike, Eiichi Nakamura
Format: Article
Language:English
Published: Korean Spine Society 2019-06-01
Series:Asian Spine Journal
Subjects:
Facet joint
Synoviocytes
Lumbar spinal stenosis
Angiopoietin-like protein 2
Interleukin-6
Online Access:http://www.asianspinejournal.org/upload/pdf/asj-2018-0178.pdf

Internet

http://www.asianspinejournal.org/upload/pdf/asj-2018-0178.pdf

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