Joint genetic analysis using variant sets reveals polygenic gene-context interactions.
Joint genetic models for multiple traits have helped to enhance association analyses. Most existing multi-trait models have been designed to increase power for detecting associations, whereas the analysis of interactions has received considerably less attention. Here, we propose iSet, a method based...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-04-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC5398484?pdf=render |