Automated Real-Time Tumor Pharmacokinetic Profiling in 3D Models: A Novel Approach for Personalized Medicine

Cancer treatment often lacks individual dose adaptation, contributing to insufficient efficacy and severe side effects. Thus, personalized approaches are highly desired. Although various analytical techniques are established to determine drug levels in preclinical models, they are limited in the aut...

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Bibliographic Details
Main Authors: Jan F. Joseph, Leonie Gronbach, Jill García-Miller, Leticia M. Cruz, Bernhard Wuest, Ulrich Keilholz, Christian Zoschke, Maria K. Parr
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/5/413