A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients

A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients

Parkinson's Disease (PD) is a neurodegenerative disorder affecting more than 10 million people worldwide. Currently, PD has no cure and no early diagnostics methods exist. Mitochondrial dysfunction is presented in the early stages of PD, and it is considered an important pathophysiology compone...

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Bibliographic Details
Main Authors: Cláudia M. Deus, Susana P. Pereira, Teresa Cunha-Oliveira, José Teixeira, Rui F. Simões, Fernando Cagide, Sofia Benfeito, Fernanda Borges, Nuno Raimundo, Paulo J. Oliveira
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Redox Biology
Subjects:
Human skin fibroblasts
Metabolism
Mitochondria
Mitochondriotropic antioxidant
Sporadic Parkinson's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721001968

Internet

http://www.sciencedirect.com/science/article/pii/S2213231721001968

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