Crystal Structure of Crataeva tapia Bark Protein (CrataBL) and Its Effect in Human Prostate Cancer Cell Lines.

A protein isolated from the bark of Crataeva tapia (CrataBL) is both a Kunitz-type plant protease inhibitor and a lectin. We have determined the amino acid sequence and three-dimensional structure of CrataBL, as well as characterized its selected biochemical and biological properties. We found two d...

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Bibliographic Details
Main Authors: Rodrigo da Silva Ferreira, Dongwen Zhou, Joana Gasperazzo Ferreira, Mariana Cristina Cabral Silva, Rosemeire Aparecida Silva-Lucca, Reinhard Mentele, Edgar Julian Paredes-Gamero, Thiago Carlos Bertolin, Maria Tereza Dos Santos Correia, Patrícia Maria Guedes Paiva, Alla Gustchina, Alexander Wlodawer, Maria Luiza Vilela Oliva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688800?pdf=render