Genomic analysis reveals the molecular basis for capsule loss in the group B Streptococcus population.

The human and bovine bacterial pathogen Streptococcus agalactiae (Group B Streptococcus, GBS) expresses a thick polysaccharide capsule that constitutes a major virulence factor and vaccine target. GBS can be classified into ten distinct serotypes differing in the chemical composition of their capsul...

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Bibliographic Details
Main Authors: Roberto Rosini, Edmondo Campisi, Matteo De Chiara, Hervé Tettelin, Daniela Rinaudo, Chiara Toniolo, Matteo Metruccio, Silvia Guidotti, Uffe B Skov Sørensen, Mogens Kilian, DEVANI Consortium, Mario Ramirez, Robert Janulczyk, Claudio Donati, Guido Grandi, Immaculada Margarit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4422693?pdf=render