Combination therapy with BRAF and MEK inhibitors for melanoma: latest evidence and place in therapy

Treatment with BRAF inhibitors such as vemurafenib or dabrafenib in patients with advanced BRAFV600 mutated melanoma has shown objective tumor responses in approximately half of the patients. However, the duration of responses is limited in a majority of these patients, with progression-free surviva...

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Bibliographic Details
Main Authors: Zeynep Eroglu, Antoni Ribas
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758834015616934