R‐spondin 2 Drives Liver Tumor Development in a Yes‐Associated Protein‐Dependent Manner

R‐spondin 2 Drives Liver Tumor Development in a Yes‐Associated Protein‐Dependent Manner

Each year, more than 25,000 people succumb to liver cancer in the United States, and this neoplasm represents the second cause of cancer‐related death globally. R‐spondins (RSPOs) are secreted regulators of Wnt signaling that function in development and promote tissue stem cell renewal. In cancer, R...

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Bibliographic Details
Main Authors: Caitlin B. Conboy, Germán L. Vélez‐Reyes, Barbara R. Tschida, Hsiangyu Hu, Gabriel Kaufmann, Nicholas Koes, Bryant Keller, Clara Alsinet, Helena Cornellà, Roser Pinyol, Juan E. Abrahante, Nuri A. Temiz, Michael A. Linden, Khalid Amin, Timothy P. Kuka, Vincent W. Keng, Josep M. Llovet, Timothy K. Starr, David A. Largaespada
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Hepatology Communications
Online Access:https://doi.org/10.1002/hep4.1422

Internet

https://doi.org/10.1002/hep4.1422

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