Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.

Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.

BACKGROUND: The increased sequencing of pathogen genomes and the subsequent availability of genome-scale functional datasets are expected to guide the experimental work necessary for target-based drug discovery. However, a major bottleneck in this has been the difficulty of capturing and integrating...

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Main Authors: Gregory J Crowther, Dhanasekaran Shanmugam, Santiago J Carmona, Maria A Doyle, Christiane Hertz-Fowler, Matthew Berriman, Solomon Nwaka, Stuart A Ralph, David S Roos, Wesley C Van Voorhis, Fernán Agüero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2927427?pdf=render

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http://europepmc.org/articles/PMC2927427?pdf=render

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