In silico identification of specialized secretory-organelle proteins in apicomplexan parasites and in vivo validation in Toxoplasma gondii.

by Zhongqiang Chen, Omar S Harb, David S Roos
Published 2008-01-01

Identification of surprisingly diverse type IV pili, across a broad range of gram-positive bacteria.

by Saheed Imam, Zhongqiang Chen, David S Roos, Mechthild Pohlschröder
Published 2011-01-01

Assessing performance of orthology detection strategies applied to eukaryotic genomes.

by Feng Chen, Aaron J Mackey, Jeroen K Vermunt, David S Roos
Published 2007-04-01

Subcellular antigen location influences T-cell activation during acute infection with Toxoplasma gondii.

by Beth Gregg, Florence Dzierszinski, Elia Tait, Kimberly A Jordan, Christopher A Hunter, David S Roos
Published 2011-01-01

Cytoskeletal components of an invasion machine--the apical complex of Toxoplasma gondii.

by Ke Hu, Jeff Johnson, Laurence Florens, Martin Fraunholz, Sapna Suravajjala, Camille DiLullo, John Yates, David S Roos, John M Murray
Published 2006-02-01

The Orphan Nuclear Receptor TLX Is an Enhancer of STAT1-Mediated Transcription and Immunity to Toxoplasma gondii.

by Daniel P Beiting, Shinya Hidano, Julie E Baggs, Jeanne M Geskes, Qun Fang, E John Wherry, Christopher A Hunter, David S Roos, Sara Cherry
Published 2015-07-01

Aspartyl Protease 5 Matures Dense Granule Proteins That Reside at the Host-Parasite Interface in Toxoplasma gondii

by Michael J. Coffey, Laura F. Dagley, Simona Seizova, Eugene A. Kapp, Giuseppe Infusini, David S. Roos, Justin A. Boddey, Andrew I. Webb, Christopher J. Tonkin
Published 2018-10-01

Differential induction of TLR3-dependent innate immune signaling by closely related parasite species.

by Daniel P Beiting, Lucia Peixoto, Natalia S Akopyants, Stephen M Beverley, E John Wherry, David A Christian, Christopher A Hunter, Igor E Brodsky, David S Roos
Published 2014-01-01

Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways.

by Stefan Baumeister, Jochen Wiesner, Armin Reichenberg, Martin Hintz, Sven Bietz, Omar S Harb, David S Roos, Maximilian Kordes, Johannes Friesen, Kai Matuschewski, Klaus Lingelbach, Hassan Jomaa, Frank Seeber
Published 2011-05-01

Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii.

by Beena John, Tajie H Harris, Elia D Tait, Emma H Wilson, Beth Gregg, Lai Guan Ng, Paulus Mrass, David S Roos, Florence Dzierszinski, Wolfgang Weninger, Christopher A Hunter
Published 2009-07-01

Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.

by Gregory J Crowther, Dhanasekaran Shanmugam, Santiago J Carmona, Maria A Doyle, Christiane Hertz-Fowler, Matthew Berriman, Solomon Nwaka, Stuart A Ralph, David S Roos, Wesley C Van Voorhis, Fernán Agüero
Published 2010-01-01

FungiDB: An Integrated Bioinformatic Resource for Fungi and Oomycetes

by Evelina Y. Basenko, Jane A. Pulman, Achchuthan Shanmugasundram, Omar S. Harb, Kathryn Crouch, David Starns, Susanne Warrenfeltz, Cristina Aurrecoechea, Christian J. Stoeckert, Jessica C. Kissinger, David S. Roos, Christiane Hertz-Fowler
Published 2018-03-01

Cytotoxic T cells mediate pathology and metastasis in cutaneous leishmaniasis.

by Fernanda O Novais, Lucas P Carvalho, Joel W Graff, Daniel P Beiting, Gordon Ruthel, David S Roos, Michael R Betts, Michael H Goldschmidt, Mary E Wilson, Camila I de Oliveira, Phillip Scott
Published 2013-01-01

ClinEpiDB: an open-access clinical epidemiology database resource encouraging online exploration of complex studies [version 1; peer review: 2 approved]

by Emmanuel Ruhamyankaka, Brian P. Brunk, Grant Dorsey, Omar S. Harb, Danica A. Helb, John Judkins, Jessica C. Kissinger, Brianna Lindsay, David S. Roos, Emmanuel James San, Christian J. Stoeckert, Jie Zheng, Sheena Shah Tomko
Published 2019-11-01

ClinEpiDB: an open-access clinical epidemiology database resource encouraging online exploration of complex studies [version 2; peer review: 2 approved]

by Emmanuel Ruhamyankaka, Brian P. Brunk, Grant Dorsey, Omar S. Harb, Danica A. Helb, John Judkins, Jessica C. Kissinger, Brianna Lindsay, David S. Roos, Emmanuel James San, Christian J. Stoeckert, Jie Zheng, Sheena Shah Tomko
Published 2020-04-01

Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy.

by Adam James Reid, Sarah J Vermont, James A Cotton, David Harris, Grant A Hill-Cawthorne, Stephanie Könen-Waisman, Sophia M Latham, Tobias Mourier, Rebecca Norton, Michael A Quail, Mandy Sanders, Dhanasekaran Shanmugam, Amandeep Sohal, James D Wasmuth, Brian Brunk, Michael E Grigg, Jonathan C Howard, John Parkinson, David S Roos, Alexander J Trees, Matthew Berriman, Arnab Pain, Jonathan M Wastling
Published 2012-01-01

CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii

by Joseph D. Lykins, Ekaterina V. Filippova, Andrei S. Halavaty, George Minasov, Ying Zhou, Ievgeniia Dubrovska, Kristin J. Flores, Ludmilla A. Shuvalova, Jiapeng Ruan, Kamal El Bissati, Sarah Dovgin, Craig W. Roberts, Stuart Woods, Jon D. Moulton, Hong Moulton, Martin J. McPhillie, Stephen P. Muench, Colin W. G. Fishwick, Elisabetta Sabini, Dhanasekaran Shanmugam, David S. Roos, Rima McLeod, Rima McLeod, Wayne F. Anderson, Huân M. Ngô, Huân M. Ngô
Published 2018-10-01

Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes

by Hernan Lorenzi, Asis Khan, Michael S. Behnke, Sivaranjani Namasivayam, Lakshmipuram S. Swapna, Michalis Hadjithomas, Svetlana Karamycheva, Deborah Pinney, Brian P. Brunk, James W. Ajioka, Daniel Ajzenberg, John C. Boothroyd, Jon P. Boyle, Marie L. Dardé, Maria A. Diaz-Miranda, Jitender P. Dubey, Heather M. Fritz, Solange M. Gennari, Brian D. Gregory, Kami Kim, Jeroen P. J. Saeij, Chunlei Su, Michael W. White, Xing-Quan Zhu, Daniel K. Howe, Benjamin M. Rosenthal, Michael E. Grigg, John Parkinson, Liang Liu, Jessica C. Kissinger, David S. Roos, L. David Sibley
Published 2016-01-01

Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites

by Yong H Woo, Hifzur Ansari, Thomas D Otto, Christen M Klinger, Martin Kolisko, Jan Michálek, Alka Saxena, Dhanasekaran Shanmugam, Annageldi Tayyrov, Alaguraj Veluchamy, Shahjahan Ali, Axel Bernal, Javier del Campo, Jaromír Cihlář, Pavel Flegontov, Sebastian G Gornik, Eva Hajdušková, Aleš Horák, Jan Janouškovec, Nicholas J Katris, Fred D Mast, Diego Miranda-Saavedra, Tobias Mourier, Raeece Naeem, Mridul Nair, Aswini K Panigrahi, Neil D Rawlings, Eriko Padron-Regalado, Abhinay Ramaprasad, Nadira Samad, Aleš Tomčala, Jon Wilkes, Daniel E Neafsey, Christian Doerig, Chris Bowler, Patrick J Keeling, David S Roos, Joel B Dacks, Thomas J Templeton, Ross F Waller, Julius Lukeš, Miroslav Oborník, Arnab Pain
Published 2015-07-01

Standardized metadata for human pathogen/vector genomic sequences.

by Vivien G Dugan, Scott J Emrich, Gloria I Giraldo-Calderón, Omar S Harb, Ruchi M Newman, Brett E Pickett, Lynn M Schriml, Timothy B Stockwell, Christian J Stoeckert, Dan E Sullivan, Indresh Singh, Doyle V Ward, Alison Yao, Jie Zheng, Tanya Barrett, Bruce Birren, Lauren Brinkac, Vincent M Bruno, Elizabet Caler, Sinéad Chapman, Frank H Collins, Christina A Cuomo, Valentina Di Francesco, Scott Durkin, Mark Eppinger, Michael Feldgarden, Claire Fraser, W Florian Fricke, Maria Giovanni, Matthew R Henn, Erin Hine, Julie Dunning Hotopp, Ilene Karsch-Mizrachi, Jessica C Kissinger, Eun Mi Lee, Punam Mathur, Emmanuel F Mongodin, Cheryl I Murphy, Garry Myers, Daniel E Neafsey, Karen E Nelson, William C Nierman, Julia Puzak, David Rasko, David S Roos, Lisa Sadzewicz, Joana C Silva, Bruno Sobral, R Burke Squires, Rick L Stevens, Luke Tallon, Herve Tettelin, David Wentworth, Owen White, Rebecca Will, Jennifer Wortman, Yun Zhang, Richard H Scheuermann
Published 2014-01-01