Differential Detection of Encapsidated versus Unencapsidated Enterovirus RNA in Samples Containing Pancreatic Enzymes—Relevance for Diabetes Studies

Differential Detection of Encapsidated versus Unencapsidated Enterovirus RNA in Samples Containing Pancreatic Enzymes—Relevance for Diabetes Studies

Using immunohistochemistry, enterovirus capsid proteins were demonstrated in pancreatic islets of patients with type 1 diabetes. Virus proteins are mainly located in beta cells, supporting the hypothesis that enterovirus infections may contribute to the pathogenesis of type 1 diabetes. In samples of...

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Bibliographic Details
Main Authors: Maarit Oikarinen, Lori Bertolet, Antonio Toniolo, Sami Oikarinen, Jutta E. Laiho, Alberto Pugliese, Richard E. Lloyd, Heikki Hyöty, the nPOD-V Study Group
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
enterovirus
virus detection
RT-PCR
pancreas
type 1 diabetes
Online Access:https://www.mdpi.com/1999-4915/12/7/747

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https://www.mdpi.com/1999-4915/12/7/747

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