Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma

Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma

In this work, hybrid compounds <b>1</b>&#8722;<b>4</b> obtained by conjugation of the non-steroidal anti-inflammatory drug diclofenac, with natural molecules endowed with antioxidant and antiproliferative activity were prepared. The antiproliferative activity of these hyb...

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Bibliographic Details
Main Authors: Silvia Tampucci, Sara Carpi, Maria Digiacomo, Beatrice Polini, Stefano Fogli, Susi Burgalassi, Marco Macchia, Paola Nieri, Clementina Manera, Daniela Monti
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
diclofenac
hybrid
squamous cell carcinoma
actinic keratosis
antiproliferative activity
nanomicelles
in vitro skin permeation/penetration
Online Access:https://www.mdpi.com/1420-3049/24/9/1793

Internet

https://www.mdpi.com/1420-3049/24/9/1793

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