Adapting Blood DNA Methylation Aging Clocks for Use in Saliva Samples With Cell-type Deconvolution

DeepMAge is a deep-learning DNA methylation aging clock that measures the organismal pace of aging with the information from human epigenetic profiles. In blood samples, DeepMAge can predict chronological age within a 2.8 years error margin, but in saliva samples, its performance is drastically redu...

Full description

Bibliographic Details
Main Authors: Fedor Galkin, Kirill Kochetov, Polina Mamoshina, Alex Zhavoronkov
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Aging
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2021.697254/full