Venous identity requires BMP signalling through ALK3

Venous identity requires BMP signalling through ALK3

The establishment of functional vasculatures requires the specification of newly formed vessels into veins and arteries. Here, Neal et al. use a combination of genetic approaches in mice and zebrafish to show that BMP signalling, via ALK3 and SMAD1/5, is required for venous specification during bloo...

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Bibliographic Details
Main Authors: Alice Neal, Svanhild Nornes, Sophie Payne, Marsha D. Wallace, Martin Fritzsche, Pakavarin Louphrasitthiphol, Robert N. Wilkinson, Kira M. Chouliaras, Ke Liu, Karen Plant, Radhika Sholapurkar, Indrika Ratnayaka, Wiebke Herzog, Gareth Bond, Tim Chico, George Bou-Gharios, Sarah De Val
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08315-w

Internet

https://doi.org/10.1038/s41467-019-08315-w

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