Carbonic Anhydrase Inhibitors as Novel Drugs against Mycobacterial β-Carbonic Anhydrases: An Update on <i>In Vitro</i> and <i>In Vivo</i> Studies

Carbonic Anhydrase Inhibitors as Novel Drugs against Mycobacterial β-Carbonic Anhydrases: An Update on <i>In Vitro</i> and <i>In Vivo</i> Studies

Mycobacteria cause a variety of diseases, such as tuberculosis, leprosy, and opportunistic diseases in immunocompromised people. The treatment of these diseases is problematic, necessitating the development of novel treatment strategies. Recently, &#946;-carbonic anhydrases (&#946;-CAs) have...

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Bibliographic Details
Main Authors: Ashok Aspatwar, Jean-Yves Winum, Fabrizio Carta, Claudiu T. Supuran, Milka Hammaren, Mataleena Parikka, Seppo Parkkila
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Molecules
Subjects:
mycobacterial diseases
β-carbonic anhydrases
<i>Mycobacterium tuberculosis</i>
drug targets
carbonic anhydrase inhibitors
in vivo inhibition
<i>in vitro</i> inhibition
Online Access:https://www.mdpi.com/1420-3049/23/11/2911

Internet

https://www.mdpi.com/1420-3049/23/11/2911

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