Experimental therapy of ovarian cancer with synthetic makaluvamine analog: in vitro and in vivo anticancer activity and molecular mechanisms of action.
The present study was designed to determine the biological effects of novel marine alkaloid analog 7-(4-fluorobenzylamino)-1,3,4,8-tetrahydropyrrolo[4,3,2-de]quinolin-8(1H)-one (FBA-TPQ) on human ovarian cancer cells for its anti-tumor potential and the underlying mechanisms as a novel chemotherapeu...
Main Authors: | Tao Chen, Yi Xu, He Guo, Yanling Liu, Pingting Hu, Xinying Yang, Xiaoguang Li, Shichao Ge, Sadanandan E Velu, Dwayaja H Nadkarni, Wei Wang, Ruiwen Zhang, Hui Wang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3108973?pdf=render |
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