An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype.
Epithelial-mesenchymal transition (EMT), a mechanism important for embryonic development, plays a critical role during malignant transformation. While much is known about transcriptional regulation of EMT, alternative splicing of several genes has also been correlated with EMT progression, but the e...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-08-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3158048?pdf=render |