Local induction of immunosuppressive CD8+ T cells in the gut-associated lymphoid tissues.

BACKGROUND: In contrast to intestinal CD4(+) regulatory T cells (T(regs)), the generation and function of immunomodulatory intestinal CD8(+) T cells is less well defined. To dissect the immunologic mechanisms of CD8(+) T cell function in the mucosa, reactivity against hemagglutinin (HA) expressed in...

Full description

Bibliographic Details
Main Authors: Diana Fleissner, Wiebke Hansen, Robert Geffers, Jan Buer, Astrid M Westendorf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2958146?pdf=render