The Role of Calcium-Permeable AMPARs in Long-Term Potentiation at Principal Neurons in the Rodent Hippocampus

The Role of Calcium-Permeable AMPARs in Long-Term Potentiation at Principal Neurons in the Rodent Hippocampus

Long-term potentiation (LTP) at hippocampal CA1 synapses is classically triggered by the synaptic activation of NMDA receptors (NMDARs). More recently, it has been shown that calcium-permeable (CP) AMPA receptors (AMPARs) can also trigger synaptic plasticity at these synapses. Here, we review this l...

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Bibliographic Details
Main Authors: Pojeong Park, Heather Kang, Thomas M. Sanderson, Zuner A. Bortolotto, John Georgiou, Min Zhuo, Bong-Kiun Kaang, Graham L. Collingridge
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
NMDA receptor
long-term potentiation
hippocampus
calcium-permeable AMPA receptor
PKA
Online Access:https://www.frontiersin.org/article/10.3389/fnsyn.2018.00042/full

Internet

https://www.frontiersin.org/article/10.3389/fnsyn.2018.00042/full

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