EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape.

EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape.

The Epstein Barr virus (EBV) contributes to the tumor phenotype through a limited set of primarily non-coding viral RNAs, including 31 mature miRNAs. Here we investigated the impact of EBV miRNAs on remodeling the tumor cell transcriptome. Strikingly, EBV miRNAs displayed exceptionally abundant expr...

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Bibliographic Details
Main Authors: Nathan Ungerleider, Whitney Bullard, Mehmet Kara, Xia Wang, Claire Roberts, Rolf Renne, Scott Tibbetts, Erik K Flemington
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009217

Internet

https://doi.org/10.1371/journal.ppat.1009217

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