Imaging perfusion deficits, arterial patency and thrombolysis safety and efficacy in acute ischaemic stroke. An observational study of the effect of advanced imaging methods in The Third International Stroke Trial (IST-3), a randomised controlled trial

Background: Intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) improves outcome after an ischaemic stroke but increases the risk of intracranial haemorrhage. Restricting rt-PA to patients with salvageable tissue, or arterial occlusion, might reduce risk, increase benefit...

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Bibliographic Details
Main Authors: Joanna M Wardlaw, Trevor Carpenter, Eleni Sakka, Grant Mair, Geoff Cohen, Kirsten Shuler, Jeb M Palmer, Karen Innes, Peter A Sandercock
Format: Article
Language:English
Published: NIHR Journals Library 2014-07-01
Series:Efficacy and Mechanism Evaluation
Online Access:https://doi.org/10.3310/eme01010