The HIV-1 capsid and reverse transcription

Abstract The viral capsid plays a key role in HIV-1 reverse transcription. Recent studies have demonstrated that the small molecule IP6 dramatically enhances reverse transcription in vitro by stabilizing the viral capsid. Reverse transcription results in marked changes in the biophysical properties...

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Bibliographic Details
Main Authors: Christopher Aiken, Itay Rousso
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Retrovirology
Subjects:
IP6
Online Access:https://doi.org/10.1186/s12977-021-00566-0