IgM and IgA augmented autoantibody signatures improve early‐stage detection of colorectal cancer prior to nodal and distant spread

Abstract Objectives Tumor‐associated autoantibodies (AAbs) in individuals with cancer can precede clinical diagnosis by several months to years. The objective of this study was to determine whether the primary immune response in form of IgM and gut mucosa‐associated IgA can aid IgG AAbs in the detec...

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Bibliographic Details
Main Authors: Md Saiful Islam Roney, Catharine Lanagan, Yong Hua Sheng, Karen Lawler, Christopher Schmidt, Nam‐Trung Nguyen, Jakob Begun, Gregor Stefan Kijanka
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
IgA
IgM
Online Access:https://doi.org/10.1002/cti2.1330