Plasma Amyloid-Beta Levels in a Pre-Symptomatic Dutch-Type Hereditary Cerebral Amyloid Angiopathy Pedigree: A Cross-Sectional and Longitudinal Investigation

Plasma Amyloid-Beta Levels in a Pre-Symptomatic Dutch-Type Hereditary Cerebral Amyloid Angiopathy Pedigree: A Cross-Sectional and Longitudinal Investigation

Plasma amyloid-beta (Aβ) has long been investigated as a blood biomarker candidate for Cerebral Amyloid Angiopathy (CAA), however previous findings have been inconsistent which could be attributed to the use of less sensitive assays. This study investigates plasma Aβ alterations between pre-symptoma...

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Bibliographic Details
Main Authors: Pratishtha Chatterjee, Michelle Tegg, Steve Pedrini, Anne M. Fagan, Chengjie Xiong, Abhay K. Singh, Kevin Taddei, Samantha Gardener, Colin L. Masters, Peter R. Schofield, Gerhard Multhaup, Tammie L. S. Benzinger, John C. Morris, Randall J. Bateman, Steven M. Greenberg, Mark A. van Buchem, Erik Stoops, Hugo Vanderstichele, Charlotte E. Teunissen, Graeme J. Hankey, Marieke J. H. Wermer, Hamid R. Sohrabi, Ralph N. Martins, the Dominantly Inherited Alzheimer Network
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
amyloid-beta
plasma amyloid-beta
blood biomarkers
cerebral amyloid angiopathy
early diagnosis
hereditary cerebral haemorrhage with amyloidosis—Dutch type
Online Access:https://www.mdpi.com/1422-0067/22/6/2931

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https://www.mdpi.com/1422-0067/22/6/2931

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