Protein Phosphatase Sit4 Affects Lipid Droplet Synthesis and Soraphen A Resistance Independent of Its Role in Regulating Elongator Dependent tRNA Modification

The protein phosphatase Sit4 has been shown to be required for lipogenesis and resistance against the acetyl-CoA carboxylase inhibitor soraphen A. Since Sit4 is also required for biosynthesis of Elongator dependent tRNA modifications such as 5-methoxycarbonylmethyluridine (mcm5U), we investigated th...

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Bibliographic Details
Main Authors: Bruno Leonardo Bozaquel-Morais, Leonie Vogt, Valentina D’Angelo, Raffael Schaffrath, Roland Klassen, Mónica Montero-Lomelí
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/8/3/49