Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner

Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner

Broadly neutralizing antibodies that recognize the conserved hemagglutinin (HA) stalk have emerged as exciting new biotherapeutic tools to combat seasonal and pandemic influenza viruses. Our general understanding of the mechanisms by which stalk-specific antibodies achieve protection is rapidly evol...

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Bibliographic Details
Main Authors: Caitlin E. Mullarkey, Mark J. Bailey, Diana A. Golubeva, Gene S. Tan, Raffael Nachbagauer, Wenqian He, Kyle E. Novakowski, Dawn M. Bowdish, Matthew S. Miller, Peter Palese
Format: Article
Language:English
Published: American Society for Microbiology 2016-10-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/5/e01624-16

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http://mbio.asm.org/cgi/content/full/7/5/e01624-16

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