Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism

Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism

Abstract Background Dietary restriction (DR), a reduction in food intake without malnutrition, increases most aspects of health during aging and extends lifespan in diverse species, including rodents. However, the mechanisms by which DR interacts with the aging process to improve health in old age a...

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Bibliographic Details
Main Authors: Oliver Hahn, Sebastian Grönke, Thomas M. Stubbs, Gabriella Ficz, Oliver Hendrich, Felix Krueger, Simon Andrews, Qifeng Zhang, Michael J. Wakelam, Andreas Beyer, Wolf Reik, Linda Partridge
Format: Article
Language:English
Published: BMC 2017-03-01
Series:Genome Biology
Subjects:
Dietary Restriction
Gene Body
Differential Methylation
Methylation Difference
Hepatic Insulin Resistance
Online Access:http://link.springer.com/article/10.1186/s13059-017-1187-1

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http://link.springer.com/article/10.1186/s13059-017-1187-1

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