Mesenchymal Stromal Cell‐Seeded Biomimetic Scaffolds as a Factory of Soluble RANKL in Rankl‐Deficient Osteopetrosis

Mesenchymal Stromal Cell‐Seeded Biomimetic Scaffolds as a Factory of Soluble RANKL in Rankl‐Deficient Osteopetrosis

Abstract Biomimetic scaffolds are extremely versatile in terms of chemical composition and physical properties, which can be defined to accomplish specific applications. One property that can be added is the production/release of bioactive soluble factors, either directly from the biomaterial, or fr...

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Bibliographic Details
Main Authors: Ciro Menale, Elisabetta Campodoni, Eleonora Palagano, Stefano Mantero, Marco Erreni, Antonio Inforzato, Elena Fontana, Francesca Schena, Rob van't Hof, Monica Sandri, Anna Tampieri, Anna Villa, Cristina Sobacchi
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Stem Cells Translational Medicine
Subjects:
Mesenchymal stromal cell
RANKL
Cell therapy
Gene therapy
Biomimetic scaffold
Osteopetrosis
Online Access:https://doi.org/10.1002/sctm.18-0085

Internet

https://doi.org/10.1002/sctm.18-0085

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