The RANKL-RANK Axis: A Bone to Thymus Round Trip

by Cristina Sobacchi, Cristina Sobacchi, Ciro Menale, Ciro Menale, Anna Villa, Anna Villa
Published 2019-03-01

Innovative Cell-Based Therapies and Conditioning to Cure RAG Deficiency

by Anna Villa, Anna Villa, Valentina Capo, Valentina Capo, Maria Carmina Castiello, Maria Carmina Castiello
Published 2020-11-01

Autosomal recessive osteopetrosis: mechanisms and treatments

by Sara Penna, Anna Villa, Valentina Capo
Published 2021-05-01

Soluble Factors on Stage to Direct Mesenchymal Stem Cells Fate

by Cristina Sobacchi, Cristina Sobacchi, Eleonora Palagano, Eleonora Palagano, Anna Villa, Anna Villa, Ciro Menale, Ciro Menale
Published 2017-05-01

One Disease, Many Genes: Implications for the Treatment of Osteopetroses

by Sara Penna, Sara Penna, Valentina Capo, Eleonora Palagano, Eleonora Palagano, Cristina Sobacchi, Cristina Sobacchi, Anna Villa, Anna Villa
Published 2019-02-01

3D Bone Biomimetic Scaffolds for Basic and Translational Studies with Mesenchymal Stem Cells

by Cristina Sobacchi, Marco Erreni, Dario Strina, Eleonora Palagano, Anna Villa, Ciro Menale
Published 2018-10-01

Non-genotoxic conditioning to overcome transplant-related toxicity in oc/oc osteopetrotic mouse model

by Valentina Capo, Sara Penna, Ludovica Santi, Andrea Cappelleri, Stefano Mantero, Eugenio Scanziani, Anna Villa
Published 2021-04-01

Gut Microbiota–Host Interactions in Inborn Errors of Immunity

by Riccardo Castagnoli, Francesca Pala, Marita Bosticardo, Amelia Licari, Ottavia M. Delmonte, Anna Villa, Gian Luigi Marseglia, Luigi Daniele Notarangelo
Published 2021-01-01

Development of central nervous system autoimmunity is impaired in the absence of Wiskott-Aldrich syndrome protein.

by Marita Bosticardo, Silvia Musio, Elena Fontana, Stefano Angiari, Elena Draghici, Gabriela Constantin, Pietro L Poliani, Rosetta Pedotti, Anna Villa
Published 2014-01-01

Generation of 3 clones of induced pluripotent stem cells (iPSCs) from a patient affected by Autosomal Recessive Osteopetrosis due to mutations in TCIRG1 gene.

by Gaetana Lanzi, Rosalba Monica Ferraro, Stefania Masneri, Giovanna Piovani, Chiara Barisani, Cristina Sobacchi, Anna Villa, Paolo Vezzoni, Silvia Giliani
Published 2020-01-01

RANKL Cytokine: From Pioneer of the Osteoimmunology Era to Cure for a Rare Disease

by Nadia Lo Iacono, Alessandra Pangrazio, Mario Abinun, Robbert Bredius, Marco Zecca, Harry C. Blair, Paolo Vezzoni, Anna Villa, Cristina Sobacchi
Published 2013-01-01

In Vivo Chronic Stimulation Unveils Autoreactive Potential of Wiskott–Aldrich Syndrome Protein-Deficient B Cells

by Anna Villa, Anna Villa, Marita Bosticardo, Maria Carmina Castiello, Francesca Pala, Lucia Sereni, Lucia Sereni, Elena Draghici, Donato Inverso, Aisha V. Sauer, Francesca Schena, Elena Fontana, Enrico Radaelli, Paolo Uva, Karla E. Cervantes-Luevano, Federica Benvenuti, Pietro L. Poliani, Matteo Iannacone, Matteo Iannacone, Matteo Iannacone, Elisabetta Traggiai
Published 2017-05-01

Investigation of the bone damage in mucopolysaccharidosis type I Hurler Syndrome: Pathophysiological mechanisms and the impact of ex vivo gene therapy

by Sara Penna, Stefania Crippa, Valentina Capo, Ludovica Santi, Roberto Bosotti, Mara Riminucci, Alessandro Corsi, Marta Serafini, Bernhard Gentner, Alessandro Aiuti, Maria Ester Bernardo, Anna Villa
Published 2020-10-01

Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients

by Genni Enza Marcovecchio, Francesca Ferrua, Francesca Ferrua, Francesca Ferrua, Elena Fontana, Elena Fontana, Stefano Beretta, Marco Genua, Ileana Bortolomai, Anastasia Conti, Davide Montin, Davide Montin, Maria Teresa Cascarano, Sonia Bergante, Veronica D’Oria, Alessandro Giamberti, Donato Amodio, Donato Amodio, Caterina Cancrini, Caterina Cancrini, Adriano Carotti, Raffaella Di Micco, Ivan Merelli, Marita Bosticardo, Marita Bosticardo, Anna Villa, Anna Villa
Published 2021-06-01

Chromosome Transplantation: A Possible Approach to Treat Human X-linked Disorders

by Marianna Paulis, Lucia Susani, Alessandra Castelli, Teruhiko Suzuki, Takahiko Hara, Letizia Straniero, Stefano Duga, Dario Strina, Stefano Mantero, Elena Caldana, Lucia Sergi Sergi, Anna Villa, Paolo Vezzoni
Published 2020-06-01

Mesenchymal Stromal Cell‐Seeded Biomimetic Scaffolds as a Factory of Soluble RANKL in Rankl‐Deficient Osteopetrosis

by Ciro Menale, Elisabetta Campodoni, Eleonora Palagano, Stefano Mantero, Marco Erreni, Antonio Inforzato, Elena Fontana, Francesca Schena, Rob van't Hof, Monica Sandri, Anna Tampieri, Anna Villa, Cristina Sobacchi
Published 2019-01-01

Thymic Epithelium Abnormalities in DiGeorge and Down Syndrome Patients Contribute to Dysregulation in T Cell Development

by Genni Enza Marcovecchio, Genni Enza Marcovecchio, Ileana Bortolomai, Ileana Bortolomai, Francesca Ferrua, Francesca Ferrua, Francesca Ferrua, Elena Fontana, Elena Fontana, Luisa Imberti, Erika Conforti, Donato Amodio, Donato Amodio, Sonia Bergante, Giulia Macchiarulo, Giulia Macchiarulo, Veronica D'Oria, Francesca Conti, Silvia Di Cesare, Georgia Fousteri, Adriano Carotti, Alessandro Giamberti, Pietro Luigi Poliani, Luigi D. Notarangelo, Caterina Cancrini, Caterina Cancrini, Anna Villa, Anna Villa, Marita Bosticardo, Marita Bosticardo
Published 2019-03-01

Exploitation of circulating CD34+ cells and non-genotoxic conditioning to overcome major limitations to treatment for autosomal recessive osteopetrosis

by Valentina Capo, Sara Penna, Ivan Merelli, Matteo Barcella, Serena Scala, Luca Basso-Ricci, Elena Draghici, Eleonora Palagano, Erika Zonari, Paolo Uva, Roberto Cusano, Alessandro Aiuti, Francesca Ficara, Cristina Sobacchi, Bernhard Gentner, Anna Villa
Published 2020-10-01

Quantitation of the Rank-Rankl Axis in Primary Biliary Cholangitis.

by Ana Lleo, Zhaolian Bian, Haiyan Zhang, Qi Miao, Fang Yang, Yanshen Peng, Xiaoyu Chen, Ruqi Tang, Qixia Wang, Dekai Qiu, Jingyuan Fang, Cristina Sobacchi, Anna Villa, Luca Di Tommaso, Massimo Roncalli, M Eric Gershwin, Xiong Ma, Pietro Invernizzi
Published 2016-01-01

Generation of an immunodeficient mouse model of tcirg1-deficient autosomal recessive osteopetrosis

by Eleonora Palagano, Sharon Muggeo, Laura Crisafulli, Irina L. Tourkova, Dario Strina, Stefano Mantero, Elena Fontana, Silvia L. Locatelli, Marta Monari, Emanuela Morenghi, Carmelo Carlo-Stella, John B. Barnett, Harry C. Blair, Paolo Vezzoni, Anna Villa, Cristina Sobacchi, Francesca Ficara
Published 2020-06-01