DNA-PK target identification reveals novel links between DNA repair signaling and cytoskeletal regulation.

DNA-PK target identification reveals novel links between DNA repair signaling and cytoskeletal regulation.

The DNA-dependent protein kinase (DNA-PK) may function as a key signaling kinase in various cellular pathways other than DNA repair. Using a two-dimensional gel electrophoresis approach and stable DNA double-strand break-mimicking molecules (Dbait32Hc) to activate DNA-PK in the nucleus and cytoplasm...

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Bibliographic Details
Main Authors: Ewa Kotula, Wolfgang Faigle, Nathalie Berthault, Florent Dingli, Damarys Loew, Jian-Sheng Sun, Marie Dutreix, Maria Quanz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3840018?pdf=render

Internet

http://europepmc.org/articles/PMC3840018?pdf=render

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