Metabolomics to unveil and understand phenotypic diversity between pathogen populations.

Leishmaniasis is a debilitating disease caused by the parasite Leishmania. There is extensive clinical polymorphism, including variable responsiveness to treatment. We study Leishmania donovani parasites isolated from visceral leishmaniasis patients in Nepal that responded differently to antimonial...

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Main Authors: Ruben t'Kindt, Richard A Scheltema, Andris Jankevics, Kirstyn Brunker, Suman Rijal, Jean-Claude Dujardin, Rainer Breitling, David G Watson, Graham H Coombs, Saskia Decuypere
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2994915?pdf=render