The autophagy protein ATG9A promotes HIV-1 infectivity

Abstract Background Nef is a multifunctional accessory protein encoded by HIV-1, HIV-2 and SIV that plays critical roles in viral pathogenesis, contributing to viral replication, assembly, budding, infectivity and immune evasion, through engagement of various host cell pathways. Results To gain a be...

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Bibliographic Details
Main Authors: Elodie Mailler, Abdul A. Waheed, Sang-Yoon Park, David C. Gershlick, Eric O. Freed, Juan S. Bonifacino
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Retrovirology
Subjects:
Nef
Online Access:http://link.springer.com/article/10.1186/s12977-019-0480-3