A phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease of substantial phenotypic heterogeneity in different ethnic groups. Here, using data from a multi-ethnic cohort, the authors describe an approach based on clinical and molecular data to subtype SLE patients into three clusters of severity.

Bibliographic Details
Main Authors: Cristina M. Lanata, Ishan Paranjpe, Joanne Nititham, Kimberly E. Taylor, Milena Gianfrancesco, Manish Paranjpe, Shan Andrews, Sharon A. Chung, Brooke Rhead, Lisa F. Barcellos, Laura Trupin, Patricia Katz, Maria Dall’Era, Jinoos Yazdany, Marina Sirota, Lindsey A. Criswell
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11845-y