Down-Regulation of Laminin (LN)- α5 is Associated with Preeclampsia and Impairs Trophoblast Cell Viability and Invasiveness Through PI3K Signaling Pathway

Down-Regulation of Laminin (LN)- α5 is Associated with Preeclampsia and Impairs Trophoblast Cell Viability and Invasiveness Through PI3K Signaling Pathway

Background/Aims: Preeclampsia (PE) is a gestational disorder defined as hypertension and proteinuria, which is deemed a major cause of maternal and neonatal mortality and morbidity worldwide. The aim of this study was to investigate the expression patterns of placental laminin (LN)-α5 expression in...

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Bibliographic Details
Main Authors: Xue Mei Zhang, Xi Xiong, Chao Tong, Qin Li, Shuai Huang, Qing Shu Li, Ya Ming Liu, Hai Ying Li, Phillip Baker, Nan Shan, Hong Bo Qi
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Laminin (LN)- α5
Trophoblast
Preeclampsia
PI3K signaling pathway
Online Access:https://www.karger.com/Article/FullText/495822

Internet

https://www.karger.com/Article/FullText/495822

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