Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer.

The International HapMap project has made publicly available extensive genotypic data on a number of lymphoblastoid cell lines (LCLs). Building on this resource, many research groups have generated a large amount of phenotypic data on these cell lines to facilitate genetic studies of disease risk or...

Full description

Bibliographic Details
Main Authors: Hae Kyung Im, Eric R Gamazon, Amy L Stark, R Stephanie Huang, Nancy J Cox, M Eileen Dolan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3276560?pdf=render