The histone H3 lysine-27 demethylase UTX plays a critical role in colorectal cancer cell proliferation

The histone H3 lysine-27 demethylase UTX plays a critical role in colorectal cancer cell proliferation

Abstract Background Ubiquitously transcribed tetratricopeptide repeat, X chromosome (UTX) is an H3K27me3 demethylase, a permissive mark associated with active gene transcription. UTX has been linked to various human cancers. Colorectal cancer (CRC) ranks 3rd among the most common cancers worldwide....

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Bibliographic Details
Main Authors: Xin Tang, Wenwei Cai, Jing Cheng, Ping Lu, Shaojun Ma, Chaoting Chen, Yi Chen, Yun Sun, Caofeng Wang, Ping Hu, Xiaomin Lv, G. Sun, Yu Wang, Jing Sheng
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Cancer Cell International
Subjects:
UTX
CRC
Proliferation
KIF14
AKT
Online Access:http://link.springer.com/article/10.1186/s12935-019-0841-y

Internet

http://link.springer.com/article/10.1186/s12935-019-0841-y

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