Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malaria.

Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malaria.

The objective of this study was to determine the appropriate dose of artesunate for use in a fixed dose combination therapy with chlorproguanil-dapsone (CPG-DDS) for the treatment of uncomplicated falciparum malaria.Open-label clinical trial comparing CPG-DDS alone or with artesunate 4, 2, or 1 mg/k...

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Bibliographic Details
Main Authors: Daniel G Wootton, Hyginus Opara, Giancarlo A Biagini, Maxwell K Kanjala, Stephan Duparc, Paula L Kirby, Mary Woessner, Colin Neate, Maggie Nyirenda, Hannah Blencowe, Queen Dube-Mbeye, Thomas Kanyok, Stephen Ward, Malcolm Molyneux, Sam Dunyo, Peter A Winstanley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2258152?pdf=render

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http://europepmc.org/articles/PMC2258152?pdf=render

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