Hidden Structural Modules in a Cooperative RNA Folding Transition

Summary: Large-scale, cooperative rearrangements underlie the functions of RNA in RNA-protein machines and gene regulation. To understand how such rearrangements are orchestrated, we used high-throughput chemical footprinting to dissect a seemingly concerted rearrangement in P5abc RNA, a paradigm of...

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Bibliographic Details
Main Authors: Brant Gracia, Hashim M. Al-Hashimi, Namita Bisaria, Rhiju Das, Daniel Herschlag, Rick Russell
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718303115