Epigenetic reprogramming in Mist1(-/-) mice predicts the molecular response to cerulein-induced pancreatitis.

Epigenetic reprogramming in Mist1(-/-) mice predicts the molecular response to cerulein-induced pancreatitis.

Gene expression is affected by modifications to histone core proteins within chromatin. Changes in these modifications, or epigenetic reprogramming, can dictate cell fate and promote susceptibility to disease. The goal of this study was to determine the extent of epigenetic reprogramming in response...

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Bibliographic Details
Main Authors: Rashid Mehmood, Gabor Varga, Sonali Q Mohanty, Scott W Laing, Yuefeng Lu, Charis L Johnson, Alexei Kharitonenkov, Christopher L Pin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3897368?pdf=render

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http://europepmc.org/articles/PMC3897368?pdf=render

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