Warfarin Anticoagulation Therapy in Caribbean Hispanics of Puerto Rico: A Candidate Gene Association Study

Warfarin Anticoagulation Therapy in Caribbean Hispanics of Puerto Rico: A Candidate Gene Association Study

Existing algorithms account for ~50% of observed variance in warfarin dose requirements after including common polymorphisms. However, they do not perform as well in populations other than Caucasians, in part because some ethno-specific genetic variants are overlooked. The objective of the present s...

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Bibliographic Details
Main Authors: Karla Claudio-Campos, Aurora Labastida, Alga Ramos, Andrea Gaedigk, Jessicca Renta-Torres, Dariana Padilla, Giselle Rivera-Miranda, Stuart A. Scott, Gualberto Ruaño, Carmen L. Cadilla, Jorge Duconge-Soler
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Pharmacology
Subjects:
pharmacogenetics
warfarin
Caribbean Hispanics
admixture
next-generation sequencing
genotyping
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00347/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00347/full

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