Rift Valley fever phlebovirus NSs protein core domain structure suggests molecular basis for nuclear filaments

Rift Valley fever phlebovirus NSs protein core domain structure suggests molecular basis for nuclear filaments

Rift Valley fever phlebovirus (RVFV) is a clinically and economically important pathogen increasingly likely to cause widespread epidemics. RVFV virulence depends on the interferon antagonist non-structural protein (NSs), which remains poorly characterized. We identified a stable core domain of RVFV...

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Bibliographic Details
Main Authors: Michal Barski, Benjamin Brennan, Ona K Miller, Jane A Potter, Swetha Vijayakrishnan, David Bhella, James H Naismith, Richard M Elliott, Ulrich Schwarz-Linek
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
Rift valley fever virus
X-ray crystallography
virulence factor
Online Access:https://elifesciences.org/articles/29236

Internet

https://elifesciences.org/articles/29236

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