Lack of association between intact/deletion polymorphisms of the APOBEC3B gene and HIV-1 risk.

The human APOBEC3 family of proteins potently restricts HIV-1 replication APOBEC3B, one of the family genes, is frequently deleted in human populations. Two previous studies reached inconsistent conclusions regarding the effects of APOBEC3B loss on HIV-1 acquisition and pathogenesis. Therefore, it w...

Full description

Bibliographic Details
Main Authors: Mayumi Imahashi, Taisuke Izumi, Dai Watanabe, Junji Imamura, Kazuhiro Matsuoka, Hirotaka Ode, Takashi Masaoka, Kei Sato, Noriyo Kaneko, Seiichi Ichikawa, Yoshio Koyanagi, Akifumi Takaori-Kondo, Makoto Utsumi, Yoshiyuki Yokomaku, Takuma Shirasaka, Wataru Sugiura, Yasumasa Iwatani, Tomoki Naoe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3965477?pdf=render