ARKS: chromosome-scale scaffolding of human genome drafts with linked read kmers

ARKS: chromosome-scale scaffolding of human genome drafts with linked read kmers

Abstract Background The long-range sequencing information captured by linked reads, such as those available from 10× Genomics (10xG), helps resolve genome sequence repeats, and yields accurate and contiguous draft genome assemblies. We introduce ARKS, an alignment-free linked read genome scaffolding...

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Bibliographic Details
Main Authors: Lauren Coombe, Jessica Zhang, Benjamin P. Vandervalk, Justin Chu, Shaun D. Jackman, Inanc Birol, René L. Warren
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Bioinformatics
Subjects:
10× Genomics Chromium
ARKS
ARCS
Next-generation sequencing
de novo assembly
Genome scaffolding
Online Access:http://link.springer.com/article/10.1186/s12859-018-2243-x

Internet

http://link.springer.com/article/10.1186/s12859-018-2243-x

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