Exploring the Pathogenesis of Alzheimer Disease in Basal Forebrain Cholinergic Neurons: Converging Insights From Alternative Hypotheses

Exploring the Pathogenesis of Alzheimer Disease in Basal Forebrain Cholinergic Neurons: Converging Insights From Alternative Hypotheses

Alzheimer disease (AD) represents an oncoming epidemic that without an effective treatment promises to exact extraordinary financial and emotional burdens (Apostolova, 2016). Studies of pathogenesis are essential for defining critical molecular and cellular events and for discovering therapies to pr...

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Bibliographic Details
Main Authors: Xu-Qiao Chen, William C. Mobley
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer disease
Down syndrome
BFCNs
Aβ
NGF
signaling endosome
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00446/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.00446/full

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