Imputation of canine genotype array data using 365 whole-genome sequences improves power of genome-wide association studies.

Imputation of canine genotype array data using 365 whole-genome sequences improves power of genome-wide association studies.

Genomic resources for the domestic dog have improved with the widespread adoption of a 173k SNP array platform and updated reference genome. SNP arrays of this density are sufficient for detecting genetic associations within breeds but are underpowered for finding associations across multiple breeds...

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Bibliographic Details
Main Authors: Jessica J Hayward, Michelle E White, Michael Boyle, Laura M Shannon, Margret L Casal, Marta G Castelhano, Sharon A Center, Vicki N Meyers-Wallen, Kenneth W Simpson, Nathan B Sutter, Rory J Todhunter, Adam R Boyko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008003

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https://doi.org/10.1371/journal.pgen.1008003

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