Dopaminergic and Opioid Pathways Associated with Impulse Control Disorders in Parkinson’s Disease

Dopaminergic and Opioid Pathways Associated with Impulse Control Disorders in Parkinson’s Disease

IntroductionImpulse control disorders (ICDs) are frequent non-motor symptoms in Parkinson’s disease (PD), with potential negative effects on the quality of life and social functioning. ICDs are closely associated with dopaminergic therapy, and genetic polymorphisms in several neurotransmitter pathwa...

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Bibliographic Details
Main Authors: Aleksander H. Erga, Ingvild Dalen, Anastasia Ushakova, Janete Chung, Charalampos Tzoulis, Ole Bjørn Tysnes, Guido Alves, Kenn Freddy Pedersen, Jodi Maple-Grødem
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Neurology
Subjects:
Parkinson’s disease
impulse control disorders
addiction
elastic net
OPRK1
DRD1
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2018.00109/full

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http://journal.frontiersin.org/article/10.3389/fneur.2018.00109/full

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