Soluble Wood Smoke Extract Promotes Barrier Dysfunction in Alveolar Epithelial Cells through a MAPK Signaling Pathway

Soluble Wood Smoke Extract Promotes Barrier Dysfunction in Alveolar Epithelial Cells through a MAPK Signaling Pathway

Abstract Wildfire smoke induces acute pulmonary distress and is of particular concern to risk groups such as the sick and elderly. Wood smoke (WS) contains many of the same toxic compounds as those found in cigarette smoke (CS) including polycyclic aromatic hydrocarbons, carbon monoxide, and free ra...

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Bibliographic Details
Main Authors: Matthew R. Zeglinski, Christopher T. Turner, Rui Zeng, Carley Schwartz, Stephanie Santacruz, Megan A. Pawluk, Hongyan Zhao, Arthur W. H. Chan, Christopher Carlsten, David J. Granville
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-46400-8

Internet

https://doi.org/10.1038/s41598-019-46400-8

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