Patients with High-Grade Gliomas Harboring Deletions of Chromosomes 9p and 10q Benefit from Temozolomide Treatment

Patients with High-Grade Gliomas Harboring Deletions of Chromosomes 9p and 10q Benefit from Temozolomide Treatment

Surgical cure of glioblastomas is virtually impossible and their clinical course is mainly determined by the biologic behavior of the tumor cells and their response to radiation and chemotherapy. We investigated whether response to temozolomide (TMZ) chemotherapy differs in subsets of malignant gli...

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Bibliographic Details
Main Authors: Silke Wemmert, Ralf Ketter, Jorg Rahnenfuhrer, Niko Beerenwinkel, Martin Strowitzki, Wolfgang Feiden, Christian Hartmann, Thomas Lengauer, Florian Stockhammer, Klaus D. Zang, Eckart Meese, Wolf-Ingo Steudel, Andreas von Deimling, Steffi Urbschat
Format: Article
Language:English
Published: Elsevier 2005-10-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
CGH
LOH
glioblastoma multiforme
survival
TMZ
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605801125

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http://www.sciencedirect.com/science/article/pii/S1476558605801125

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