An elevated polyclonal free light chain level reflects a strong interferon signature in patients with systemic autoimmune diseases
High amount of polyclonal free light chains (FLC) are reported in systemic autoimmune diseases (SAD) and we took advantage of the PRECISESADS study to better characterize them. Serum FLC levels were explored in 1979 patients with SAD (RA, SLE, SjS, Scl, APS, UCTD, MCTD) and 614 healthy controls. Inf...
Main Authors: | Eléonore Bettacchioli, Christelle Le Gaffric, Margaux Mazeas, Maria Orietta Borghi, Johan Frostegard, Guillermo Barturen, Zuzanna Makowska, Sepideh Babei, Ralf Lesche, Pier Luigi Meroni, Marta E. Alarcon-Riquelme, Yves Renaudineau |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Journal of Translational Autoimmunity |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589909021000101 |
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