Identification of Catalposide Metabolites in Human Liver and Intestinal Preparations and Characterization of the Relevant Sulfotransferase, UDP-glucuronosyltransferase, and Carboxylesterase Enzymes

Identification of Catalposide Metabolites in Human Liver and Intestinal Preparations and Characterization of the Relevant Sulfotransferase, UDP-glucuronosyltransferase, and Carboxylesterase Enzymes

Catalposide, an active component of <i>Veronica</i> species such as <i>Catalpa ovata</i> and <i>Pseudolysimachion lingifolium</i>, exhibits anti-inflammatory, antinociceptic, anti-oxidant, hepatoprotective, and cytostatic activities. We characterized the in vitro...

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Bibliographic Details
Main Authors: Deok-Kyu Hwang, Ju-Hyun Kim, Yongho Shin, Won-Gu Choi, Sunjoo Kim, Yong-Yeon Cho, Joo Young Lee, Han Chang Kang, Hye Suk Lee
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Pharmaceutics
Subjects:
catalposide
in vitro human metabolism
UDP-glucuronosyltransferase
sulfotransferase
carboxylesterase
Online Access:https://www.mdpi.com/1999-4923/11/7/355

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https://www.mdpi.com/1999-4923/11/7/355

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